S (continued)
- Sparkster
- Spartan X 2
- Speed Devils
- Spelunker
- Spelunker II: Yūsha e no Chōsen
- Spider-Man and the X-Men in Arcade’s Revenge
- Spider-Man vs the Kingpin
- Spider-Man: Return of the Sinister SIx
- Spider-Man: the Movie
- Splatterhouse 2
- Splatterhouse 3
- Splatterhouse Wanpaku Graffiti
- Spot Goes to Hollywood
- Spriggan Powered
- Spy Hunter
- Spy Hunter (NES)
- Sqoon
- Star Fox
- Star Fox 64
- Star Fox Adventures
- Star Fox Assault
- Star Soldier
- Star Soldier: Vanishing Earth
- Star Tropics
- Star Wars
- Star Wars - Shadows of the Empire
- Star Wars - the Empire Strikes Back
- Star Wars: Episode 1: Racer
- Star Wars: Jedi Power Battles
- Star Wars: Rogue Squadron
- Star Wars: Starfighter
- Starblade
- Starship Hector
- Steel Assault
- Steel Empire
- Steel Empire (PC)
- Stinger
- Street Fighter 2010
- Street Fighter II
- Street Fighter II Turbo
- Street Fighter II: Special Champion Edition
- Street Racer
- Street Smart
- Streets of Rage
- Streets of Rage 2
- Streets of Rage 3
- Strider
- Strider (Sega)
- Strider 2
- Strike Gunner S.T.G